Home > Blog

Gut Health and Hormones

By Published On: September 29, 2026
Gut Health and Hormones

Written by Sinéad Urwin, Functional Nutritionist and Wellness Coach

Gut Health and Hormones: Why Your Gut May Matter More Than You Think

The gut–hormone connection that can affect your energy, digestion, metabolism, mood and more

Key Takeaways

  • Your gut does far more than digest food. The gut microbiome interacts with metabolism, immune function, the nervous system and hormones.
  • Researchers are continuing to study the connection between the gut microbiome and hormones such as estrogen.
  • Gut health, stress, sleep, movement and nutrition are interconnected.
  • Supporting gut health usually starts with simple fundamentals: more plant diversity, adequate fiber, regular movement, quality sleep and stress management.
  • Probiotics and supplements aren’t a universal fix. Individual needs vary.
  • An immersive fitness and health retreat like Unite can provide the structure, nutrition, movement, recovery and stress-management support that make these healthy habits easier to practice consistently.
Have you ever thought:

“Why am I so exhausted when I’m actually sleeping?”

“Why isn’t my body responding to exercise the way it used to?”

“Why am I gaining weight when I haven’t really changed what I’m doing?”

“Why is my digestion suddenly so unpredictable?”

“Why do I feel like something is wrong when my bloodwork says everything is normal?”

For many people in midlife, the first explanation they hear is hormones. And hormones absolutely matter. Perimenopause, menopause, changes in testosterone, thyroid hormones, insulin and cortisol can all influence energy, body composition, sleep, mood and recovery.

But hormones don’t operate in isolation.

There is another system that deserves much more attention: your gut.

Your gut is home to trillions of microorganisms that interact with your immune system, metabolism, nervous system and hormones. Researchers are increasingly uncovering the ways in which the gut microbiome and endocrine system communicate with one another.

In other words, when you’re trying to understand why you don’t feel like yourself anymore, the gut may be an important part of the bigger picture.

Your Gut Is About Much More Than Digestion

When we think about gut health, we often think about bloating, constipation, diarrhea or heartburn.

But your gastrointestinal system is doing far more than digesting your lunch.

Your gut is home to a complex ecosystem of bacteria and other microorganisms known collectively as the gut microbiome. These microbes interact with the food you eat and produce compounds that can influence immune function, metabolism, inflammation and communication between the gut and brain.

Your digestive system also communicates constantly with your nervous system through what is known as the gut-brain axis.

And your gut is involved in the metabolism and recycling of hormones, particularly estrogen.

This is one reason I encourage my clients not to look at symptoms in isolation.

Bloating isn’t necessarily just bloating.

Poor sleep isn’t necessarily just poor sleep.

Weight changes aren’t necessarily just calories in versus calories out.

Sometimes the body is giving you several different clues about the same underlying systems.

The Gut–Hormone Connection

One of the most fascinating areas of research is the relationship between the gut microbiome and estrogen.

Researchers use the term estrobolome to describe the collection of gut microbial genes involved in estrogen metabolism. Your liver processes estrogen and prepares it for elimination through bile and the digestive tract.

Once estrogen reaches the gut, certain bacterial enzymes can modify it, influencing whether some of it is excreted or reabsorbed into circulation.

This means that the gut microbiome is one part of a much larger system involved in estrogen regulation.

The relationship goes both ways, too: hormones such as estrogen can also influence the gut microbiome.

Research into this relationship is still evolving, and recent reviews continue to emphasize both the potential connection and the complexity of the evidence.

Importantly, this doesn’t mean that gut bacteria are the sole cause of hormone imbalance, or that fixing your gut will “balance your hormones.” Hormone regulation is complex and influenced by age, genetics, body composition, medications, lifestyle and many other factors.

But it does mean that gut health deserves a seat at the table when we’re talking about hormones and midlife health.

What About Weight Gain and Metabolism?

This is where the conversation gets particularly interesting.

Your gut microbiome interacts with the food you eat and produces metabolites that can influence metabolic processes, inflammation and communication between the gut and other organs.

Your gut also interacts with hormones involved in appetite, digestion and blood-sugar regulation.

Research from the National Institute of Diabetes and Digestive and Kidney Diseases has also explored how diet and the gut microbiome may influence metabolism and energy balance.

But here’s something I want you to remember:

Your metabolism isn’t broken simply because your body has changed.

Midlife brings genuine physiological changes. Hormonal shifts, changes in muscle mass, sleep, stress, activity levels and eating patterns can all affect body composition and metabolic health.

Rather than responding by eating less and exercising harder, it can be more productive to look at the whole picture:

Are you eating enough protein?

Are you getting enough fiber and plant foods?

Are you strength training?

Are you sleeping?

Are you managing chronic stress?

Are you digesting and tolerating the foods you’re eating?

Are you supporting your gut microbiome?

That is a much more useful conversation than simply asking, “How do I lose weight?”

For guests navigating midlife changes, this whole-person approach also fits naturally with Unite’s fitness and health retreat for adults, where nutrition, strength training, recovery and lifestyle habits are addressed together. Unite describes its current program as an all-inclusive fitness camp and health retreat focused on fitness, nutrition and mental health.

Your Gut and Your Brain Are Talking All Day

Have you ever noticed that your stomach feels different when you’re stressed?

Maybe you lose your appetite. Maybe you suddenly need to use the bathroom. Maybe your stomach feels tight or uncomfortable.

That’s the gut-brain connection in action.

Communication between the gut and brain occurs through multiple pathways, including the vagus nerve, immune signaling, hormones and microbial metabolites. And the relationship works in both directions.

Stress can influence digestion and the gut microbiome. At the same time, signals originating in the gut can influence the brain and nervous system.

There is also a fascinating connection with serotonin. Around 90–95% of the body’s serotonin is found in the gastrointestinal tract, where it plays important roles in gut function, motility and immune signaling.

One important clarification: gut serotonin isn’t simply the same thing as the serotonin in your brain. Much of the serotonin produced in the gut does not cross the blood-brain barrier.

So rather than saying “your gut makes your happiness hormone,” it’s more accurate to say that the gut and brain are part of a highly interconnected communication system.

And that system matters.

Your Gut, Sleep and Stress Are Connected Too

This is another area where the science is evolving quickly.

Sleep and the gut microbiome appear to have a bidirectional relationship: disrupted sleep can affect the gut, while signals from the gut microbiome may also influence sleep and circadian processes.

And stress matters.

Your digestive system is designed to function differently when you’re calm than when you’re in a constant state of stress.

Think about the difference between sitting down to eat a relaxed meal with friends versus eating lunch at your desk while answering emails.

Same food.

Different physiological environment.

That doesn’t mean three deep breaths will magically cure digestive problems.

But creating a calmer transition into meals can be a simple way to support the body’s normal digestive processes.

This connection between stress, recovery and physical health is one reason a structured wellness retreat or health retreat can be helpful for people who feel stuck in a cycle of poor sleep, stress, inconsistent meals and little time for recovery.

At Unite’s wellness retreat, fitness, hiking, mindfulness, recovery and chef-prepared meals are intentionally integrated rather than treated as separate pieces.

So What Disrupts Gut Health?

Gut health isn’t determined by one food or one supplement.

It’s influenced by your overall environment and lifestyle.

Some of the factors researchers are investigating include:

  • A low-fiber, low-diversity diet
  • High intake of ultra-processed foods
  • Chronic stress
  • Poor or disrupted sleep
  • Certain medications, including antibiotics
  • Alcohol consumption
  • Low physical activity
  • Illness and infection
  • Changes in the intestinal barrier
  • The overall pattern and diversity of the foods we eat

And here’s the encouraging part:

Many of these factors are modifiable.

You don’t need to “detox” your body or follow an extreme elimination diet to begin supporting your gut.

In fact, sometimes the most powerful place to start is surprisingly simple.

5 Ways to Start Supporting Your Gut Today

1. Increase Plant Diversity

Rather than obsessing over a single “superfood,” think about variety.

Vegetables. Fruit. Beans. Lentils. Whole grains. Nuts. Seeds. Herbs and spices.

Different plants provide different types of fiber and plant compounds that interact with the microbiome.

You may have heard the recommendation to aim for 30 different plant foods each week.

Think of this as a diversity challenge rather than a pass/fail target.

Start wherever you are.

If you currently eat five different plant foods in a week, aim for eight.

Then ten.

Build from there.

2. Feed Your Gut Bacteria With Fiber

Fiber isn’t just important for keeping you regular.

It is also fuel for many of the microorganisms living in your colon.

Good sources include:

  • Beans and lentils
  • Oats
  • Whole grains
  • Berries and other fruit
  • Vegetables
  • Nuts and seeds
  • Chia and flax
  • Onions, garlic and leeks

If your current diet is low in fiber, increase it gradually.

A sudden jump in fiber can actually make bloating and gas worse for some people.

More isn’t always better if your gut isn’t ready for it.

At Unite, chef-prepared meals focus on balanced nutrition with lean proteins, vegetables and other nutrient-dense foods, making nutrition part of the daily experience rather than something guests have to navigate alone. Learn more about nutrition at Unite Fitness Retreat.

3. Experiment With Fermented Foods

Foods such as plain yogurt, kefir, sauerkraut, kimchi and miso can be an easy way to introduce fermented foods into your diet.

Start small.

A spoonful of sauerkraut alongside lunch.

Plain yogurt with berries.

A little kefir in a smoothie.

You don’t need to eat fermented foods at every meal—or force yourself to eat something that makes your digestive symptoms worse.

Pay attention to how your body responds.

4. Support Your Nervous System Before You Eat

Try this before your next meal:

  • Put your phone down.
  • Take three slow breaths.
  • Relax your shoulders.
  • Notice the food in front of you.
  • Then eat slowly enough to actually taste it.

Digestion starts before food even reaches your stomach.

The sights, smells and anticipation of food are all part of the body’s preparation for digestion.

This small ritual won’t solve every digestive problem, but it can be a useful way to shift out of “go, go, go” mode and give yourself a moment to eat with greater awareness.

5. Don’t Underestimate Sleep and Movement

Gut health doesn’t exist separately from the rest of your lifestyle.

Regular movement, resistance training, adequate sleep, stress management and a nutrient-dense diet all contribute to the environment in which your gut—and the rest of your body—has to function.

And this is one reason I love the approach at Unite.

Fitness isn’t just about burning calories.

Nutrition isn’t just about eating less.

Recovery isn’t something you do only after you’ve pushed yourself too hard.

Your body works as a system.

When you support the system as a whole, you give yourself a much better foundation for long-term health.

Why Unite Is a Good Place to Focus on Gut Health and Whole-Body Wellness

Unite Fitness Retreat isn’t a gastrointestinal clinic, and the program isn’t intended to diagnose or treat digestive disease.

What Unite does offer is something that can be very difficult to recreate at home:

a structured environment where many of the habits that support gut health and overall wellbeing happen together.

That includes:

  • Chef-prepared, nutrient-dense meals
  • Functional nutrition guidance
  • Regular strength training and movement
  • Daily outdoor activity
  • Structured hydration and meal timing
  • Mindfulness and stress-management practices
  • Yoga and mobility
  • Recovery
  • Sleep-supportive routines
  • Education around sustainable habits

Unite is an all-inclusive residential fitness retreat and health retreat in Salt Lake City, Utah, with certified trainers, functional nutritionists, therapists, life coaches and other wellness professionals working within the program.

The purpose isn’t to “heal your gut” in a week.

It’s to give you the space and structure to work on the bigger picture.

That distinction matters.

Because as Sinead points out throughout this article, gut health doesn’t exist separately from nutrition, movement, sleep, stress or the rest of your body.

Unite’s Utah setting can also help remove guests from their usual da-to-day routine. Daily outdoor movement and time in the Wasatch Mountains are part of the retreat experience. Learn more about Unite’s Salt Lake City location.

What About Probiotics and Supplements?

This is where I encourage people to slow down.

There is a huge market for products promising to “heal your gut,” “balance your hormones” or “reset your microbiome.”

The reality is considerably more nuanced.

Probiotics are not interchangeable.

Different strains have different effects, and what helps one person may not help another.

The same is true of supplements such as magnesium, omega-3s, vitamin D, glutamine and other products commonly marketed for gut health.

Supplements can have a role, but they should be considered within the context of the individual, rather than as a universal gut-health protocol.

Food, sleep, movement, stress and overall dietary pattern are still important foundations.

And if you have persistent bloating, abdominal pain, changes in bowel habits, unexplained weight loss, blood in your stool or other concerning symptoms, it’s important to speak with your healthcare provider rather than trying to self-treat with supplements.

Nutritional Counseling with Sinead

Your Gut-Health Reset: Three Things to Try This Week

You don’t need to overhaul your life tomorrow.

Instead, try these three simple experiments:

1. Count Your Plants

For seven days, write down every different plant food you eat.

Don’t worry about hitting 30.

Just see where you are—and see whether you can gradually increase your variety.

2. Add One Fermented Food

Try plain yogurt, kefir, sauerkraut, kimchi or another fermented food that you enjoy.

Start with a small amount and see how you feel.

3. Take Three Breaths Before Every Meal

Three slow breaths.

Relax your shoulders.

Put your attention on your food.

Then eat.

That’s it.

Small actions repeated consistently can be far more useful than another extreme health reset that lasts for ten days.

The Bigger Picture

If there’s one thing I want you to take away, it’s this:

Your symptoms don’t exist in isolation.

Your gut, brain, hormones, metabolism, immune system, sleep and nervous system are constantly communicating.

That doesn’t mean every symptom is caused by your gut.

It doesn’t mean hormones don’t matter.

And it certainly doesn’t mean you need to embark on another restrictive diet.

It means we need to start looking at the body as the interconnected system that it is.

Because sometimes the question isn’t:

“What’s wrong with me?”

It’s:

“What is my body trying to tell me?”

And learning how to listen may be the first step toward feeling like yourself again.

Frequently Asked Questions About Gut Health, Hormones and Wellness Retreats

What is the connection between gut health and hormones?

The gut microbiome participates in a number of metabolic processes, including pathways involved in estrogen metabolism. Researchers are studying this relationship closely, particularly in midlife and menopause, but hormone regulation is complex and gut bacteria are only one part of the picture.

What is the estrobolome?

The estrobolome refers to gut microbial genes involved in estrogen metabolism. Certain bacterial enzymes can affect how estrogen is processed and recirculated within the body. Research in this area is developing rapidly, and scientists are still working to determine its clinical significance.

Can gut health affect weight loss?

The gut microbiome interacts with food, metabolism and signaling throughout the body, but there is no single microbiome pattern that guarantees weight loss. Nutrition, muscle mass, physical activity, hormones, sleep, stress, medications and many other factors also influence body weight.

What foods can support gut health?

A diverse diet containing fruits, vegetables, beans, lentils, whole grains, nuts, seeds and other fiber-rich plant foods is a sensible foundation for many people. Fermented foods can also be incorporated when well tolerated.

Does stress affect digestion?

Yes. The digestive system and nervous system communicate closely through the gut-brain axis. Many people notice changes in appetite, bowel habits or digestive comfort during periods of significant stress.

Can a fitness or health retreat improve gut health?

A wellness retreat cannot promise to treat digestive disease or “reset” the microbiome. However, a structured fitness and health retreat can help people consistently practice behaviors associated with overall health, including balanced nutrition, regular movement, adequate sleep, stress management and recovery.

Why might Unite be helpful for someone focusing on gut health?

Unite brings several lifestyle components together in one environment: chef-prepared nutrition, functional nutrition guidance, strength training, outdoor movement, mindfulness, recovery and healthy habit education. That can be particularly useful for someone who wants to focus on whole-body wellness rather than relying on another restrictive diet or supplement.

About Sinead Urwin

Sinead Urwin is a Functional Nutritionist and Wellness Coach who helps driven women and men understand the connections between nutrition, lifestyle and the symptoms that can leave them feeling unlike themselves.

Her approach looks beyond individual symptoms to consider the bigger picture—including nutrition, digestion, sleep, stress, movement and lifestyle—to create realistic strategies that fit into real life.

Sinead brings both professional expertise and personal experience to this work. After years of high-pressure work and chronic stress contributed to her own health challenges, she began exploring nutrition, psychology and holistic wellness and ultimately changed the direction of her career.

Today, she works with people who are ready to understand their bodies, make meaningful changes and build a healthier foundation for the years ahead.

You don’t have to accept feeling exhausted, uncomfortable or unlike yourself as simply “part of getting older.”

 

This article is for educational purposes only and is not intended to diagnose or treat any medical

condition. If you have persistent or concerning symptoms, consult your physician. 

Recent Posts